الوصف

In this study, 6-(5-bromothiohen-2-yl)-2,3-dihydro-1-methyl-3-oxo-2-phenyl-1H-pyrazolo[4,3-b]pyridine-5-carbonitrile (BDPC) powder was synthesized. BDPC powder showed a polycrystalline structure, whereas the thermally evaporated films had an amorphous structure. The optical parameters such as absorption coefficient and refractive index were calculated in the spectral range 200–500 nm. Spectral distribution analysis of the absorption coefficient revealed that the films had an indirect band transitions with energy gaps of 2.57 eV and 3.5 eV. According to the single oscillator model, the oscillation energy, dispersion energy, and dielectric constant were estimated. The room-temperature current–voltage characteristics of the fabricated Au/BDPC/p-Si/Al heterojunction showed diode-like behavior. The ideality factor, the barrier height and series resistance were determined based on thermionic emission theory and

A novel organic compound containing antipyrine and thiadiazole moieties, N-(5-{[antipyrinyl-hydrazono]-cyanomethyl}-[1,3,4]thiadiazol-2-yl)-benzamide (ACTB) has been synthesized. The thermal properties, alternating current electrical conductivity (σAC) and electrical modulus of ACTB have been reported. The thermal properties were analyzed using differential scanning calorimetry and thermogravimetric measurements. The AC measurements of bulk ACTB were performed in frequency range 100 Hz–5 MHz and temperature range 303–503 K. The frequency dependence of AC conductivity is found to follow Jonscher’s universal power law with the applicability of the correlated barrier hopping model. The temperature dependence of σAC could be described in terms of Arrhenius relation with two activation energies. The activation energy decreases with increasing frequency. The dielectric relaxation behavior is explained in terms of electric modulus formalism. At relatively higher temperatures, the imaginary modulus spectra exhibit asymmetric maxima with peak-width much broader than that of the Debye peak and are skewed toward the high frequency sides of the maxima with increasing temperature. The relaxation time is calculated and exhibited thermally activated process with activation energy of 0.77 eV.

Several new pyridine derivatives were prepared via reacting the enaminoketones 1a-d with active hydrogen reagents. Reaction of the enaminoketones 1a-c with 4-acetyl-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one 2a yielded the pyridines 3a-c. Condensation of the enaminonitrile 1d with 2b-d or 3-(1,5-dimethyl-3-oxo-2-phenyl-2,3- dihydro-1H-pyrazol-4-yl)-3-oxopropanenitrile 8 give the pyridine derivatives 6a-c and 10 respectivly. Also, (E)-3- (3-(dimethylamino)acryloyl)-2H-chromen-2-one 1a reacted with active methylenes in diethyl 3-oxopentanedioate 12 and 4-methyl-6-oxo-2-thioxo-1,2,5,6-tetrahydropyridine-3-carbonitrile 15 to afford the pyridine derivatives 14 and 16 respectively.

The electrical and dielectric properties of the synthesized 2-(antipyrin-4-ylhydrazono)-2-(4-nitrophenyl)acetonitrile (AHNA) have been studied. The direct and alternating current (DC and AC) conductivities and complex dielectric constant were investigated in temperature range 303–403 K. The AC conductivity and dielectric properties of AHNA were investigated over frequency range 100 Hz–5 MHz. From DC and AC measurements, electrical conduction is found to be a thermally activated process. The frequency-dependent AC conductivity obeys Jonscher's universal power law in which the frequency exponent decreases with increasing temperature. The correlated barrier hopping (CBH) is the predominant model for describing the charge carrier transport in which the electrical parameters are evaluated. The activation energy is found to decrease with increasing frequency. The behaviors of dielectric and dielectric loss are discussed in terms of a polarization mechanism. The dielectric loss shows frequency power law from which the maximum barrier height is determined as 0.19 eV in terms of the Guintini model.

The 5-(2-phenylhydrazono)-3,3-dimethylcyclohexanone (PHDMC) is synthesized by reacting 5,5-dimethylcyclohexane-1,3-dione with 2-phenylhydrazine. Synthesized PHDMC is polycrystalline with monoclinic space group, P2₁/a. Miller’s indices values for each diffraction peak in the X-ray diffraction spectrum are calculated. Thin films of PHDMC with different thickness values (0.83–1.247μm) are prepared by thermal evaporation technique and they exhibit amorphous structure. Different vibrational modes, observed in infrared spectra of the powder and thin films, were assigned to the molecular bonding structure of PHDMC compound. The optical properties of PHDMC thin films are investigated by measuring the optical transmittance and reflectance at the normal incidence of the light in the spectral range 200–2500nm. The refractive and absorption indices of the films are found to be independent of the film thickness …

New Synthetic Routes of Functionally substituted[1,2,4][1,5-a]Triazoloquinoline, Coumarinimine, Quinoline, Chromene, Quinazoline, Pyrazoloquinazoline and Benzotriazolotriazine …

SEVERAL new functionally [1,2,4]triazolo[1,5-a]quinoline-4- …… carbonitriles (8a-c) and [1,2,4] triazolo[1,5-a]quinoline-4-carbox-amides 12a,b were prepared from Nʹ-(5,5-dimethyl-3-oxocyclohexen-1-yl)benzohydrazide (5) and arylmethylene nitriles 2a-c and 2d,e, respactively.Reacting 2-oxo-3H-indol-3-ylidene malonic acid derivatives 3a,b with 5 afforded dioxospiro [3H-indole-3,4ʹ-quinoline]-3ʹ-carbonitrile (15) and 2- oxo-[1H] indol-3-ylcyanoacetate (17), respactively.Treating 5 with the enaminoester 18 gave hexahydro-7,7-dimethyl-2,5-dioxoquinolin-3-yl]benzamide (20). Coupling of 5 with the aryl diazonium salts and heteroaryl diazonium salts gave the hydrazones (21) and tetrahydro-[1,2,4]triazolo[5,1-c] [1,2,4] benzotriazine-6-ylidene)benzohydrazide (26

Utility of Nitriles in Organic Synthesis: Synthesis of Poly-Functionaly Substituted Pyridones and Isoquinoline Derivatives. Alex. J. Pharm. Sci.